The first hypodermic needles were fashioned from animal bladders and hollow bird quills
The first hypodermic syringes were improvised from animal bladders and hollow bird quills, allowing 17th-century scientists to perform the first precise drug injections.
In the 1650s, the chemist Robert Boyle and his colleague Christopher Wren developed the first functional hypodermic needle by utilizing the natural anatomy of birds. They fashioned needles from hollow quills and attached them to animal bladders filled with opium and other tinctures. By squeezing the bladder, they could force a precise dose of medicine directly into the bloodstream of a subject, bypasssing the digestive system entirely.
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