Modern mass spectrometry can map the exact distribution of drugs within a single microscopic tissue sample
Advanced mass spectrometry now utilizes laser-assisted ionization to map the precise location of pharmaceuticals and metabolites within biological tissues at a microscopic scale of just a few micrometers.
Matrix-assisted laser desorption/ionization (MALDI) has transformed analytical chemistry by providing high-resolution molecular imaging of biological samples. This technique allows researchers to visualize exactly how a drug distributes within a single microscopic tissue slice, identifying specific metabolite concentrations that were previously invisible. The precision of these vacuum-based systems is a cornerstone of modern proteomics, enabling the development of patient-specific molecular profiling in Germany and across the 1.83 billion Euro European market.