In 1496, Christopher Columbus left his brother in charge of the first permanent European city in the Americas
In 1496, Christopher Columbus sailed back to Spain and left his brother Bartolomeo in charge of Santo Domingo, the settlement that would become the oldest continuously inhabited European city in the Americas.
Before departing for Europe on March 10, 1496, Christopher Columbus appointed his brother as the governor of the newly founded settlement of Santo Domingo. Located in the modern-day Dominican Republic, this city served as the primary headquarters for Spanish exploration in the Caribbean.
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